← Endometriose-overzicht

Referenties endometriose-dossier

Dit dossier is gebaseerd op een literatuursynthese van reviews, meta-analyses, systematische reviews en gerandomiseerde studies, met het zwaartepunt op werk uit 2025-2026. Per claim is in de hoofdstukken de PMID vermeld. Hieronder de volledige lijst.

Ontstaanshypotheses en pathogenese

• PMID 42116741 - Peritoneal Hypoxia as a Gatekeeper Between Physiologic Retrograde Menstruation and Pathologic Persistence in Endometriosis. Reproduction, 2026.
• PMID 42202667 - Free pelvic fluid detection and quantification using transvaginal ultrasound: a surrogate marker for retrograde menstruation. Reprod Biomed Online, 2026.
• PMID 42196487 - Cancer-like Hallmarks of Endometriosis: The Role of Estrogen Signaling and Stem Cell Plasticity. Int J Mol Sci, 2026.
• PMID 42177547 - Decidualization potential of endometrial mesenchymal stem cells and their role in reproductive health. Reprod Biol Endocrinol, 2026.
• PMID 42105224 - Somatic mutations in endometrial epithelium: biological insights and emerging in vitro models. Mol Hum Reprod, 2026.

Pathways

• PMID 41439725 - Targeting inflammation in endometriosis: emerging therapeutic options. Expert Opin Investig Drugs, 2025.
• PMID 41689677 - Molecular mechanisms in endometriosis: linking JAK/STAT pathway, ferroptosis, and microbial dysbiosis. Mol Biol Rep, 2026.
• PMID 41668890 - Targeting angiogenesis in endometriosis: a systematic review and network meta-analysis of VEGF-directed pharmacotherapies. Front Reprod Health, 2025.
• PMID 41683818 - The AGE-RAGE Pathway in Endometriosis: A Focused Mechanistic Review and Structured Evidence Map. Int J Mol Sci, 2026.
• PMID 42102134 - Targeting the Wnt signaling network in endometriosis: mechanistic insights and translational opportunities. Biol Reprod, 2026.
• PMID 41303437 - Mechanistic Insights into the Anti-Inflammatory and Anti-Proliferative Effects of Selected Medicinal Plants in Endometriosis. Int J Mol Sci, 2025.
• PMID 41141268 - Plant-based bioactives and oxidative stress in reproduction: anti-inflammatory and metabolic protection mechanisms. Front Nutr, 2025.

Genetica en epigenetica

• PMID 42193961 - Is Recurrent Endometriosis a Reprogrammed Disease? Molecular Persistence Beyond Surgical Clearance. Cells, 2026.
• PMID 42143138 - Whole genome methylation profiling of menstrual stem cells identifies novel biomarkers for endometriosis. Commun Med, 2026.
• PMID 42196574 - Molecular Characterization of Ovarian Endometriosis: Inflammatory, Autophagic, and Epigenetic Dysregulation (DNMT3B, H3.1). Int J Mol Sci, 2026.
• PMID 42162597 - Hypoxia-mediated epigenetic silencing of YTHDF2 promotes endometriosis progression via the NFE2L1-NF-κB axis (m6A/HDAC11). Int J Biol Macromol, 2026.
• PMID 42091420 - Histone Deacetylase 10 Inhibitors Suppress Progression of Endometriosis via IRF6 and DACH1. J Obstet Gynaecol Res, 2026.
• PMID 42095448 - Dose-Dependent Reprogramming of Chromatin Accessibility by SOX4 Drives the Transcriptional Response to Iron Overload. Adv Sci, 2026.

Risicofactoren (immuun, omgeving, microbioom, dieet)

• PMID 42023240 - Immune dysregulation in endometriosis: the T cell perspective. Front Immunol, 2026.
• PMID 42158187 - Association between bisphenols A and the risk of endometriosis: an updated meta-analysis. Front Public Health, 2026.
• PMID 42250590 - Hexachlorobenzene and chlorpyrifos, environmental pollutants that disrupt the endocrine system, promote angiogenesis associated with endometriosis. Food Chem Toxicol, 2026.
• PMID 41752750 - Gut Microbiota Alterations and Reproductive Tract Dysbiosis in Endometriosis: A Systematic Review. Medicina, 2026.
• PMID 41693858 - Gut microbiota as a key regulator in endometriosis: mechanisms, therapeutic opportunities, and future perspectives. Front Cell Infect Microbiol, 2025.
• PMID 40624721 - Dietary factors and risk for endometriosis: a Mendelian randomization analysis. Nutr Metab, 2025.

Suppletie, natuurlijke stoffen en dieet

• PMID 40288359 - Dietary Supplements for Endometriosis-Associated Pain: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials. Gynecol Obstet Invest, 2026.
• PMID 40273491 - Effect of omega-3 polyunsaturated fatty acid on endometriosis. Clinics (Sao Paulo), 2025.
• PMID 40257970 - Vitamin D for primary dysmenorrhea and endometriosis-related pain - A systematic review of registered RCTs. PLoS One, 2025.
• PMID 41683896 - Therapeutic Effects of Vitamins in Endometriosis Patients: A Systematic Review of Randomized Controlled Trials. Int J Mol Sci, 2026.
• PMID 42116278 - Causal effects of endometriosis on serum 25-hydroxyvitamin D: Evidence from Mendelian randomization study. Medicine, 2026.
• PMID 41073678 - Efficacy of Organic Selenium Supplementation on Endometrioma Regression and Pain in Women With Endometriosis: A Triple-Blind RCT. Biol Trace Elem Res, 2026.
• PMID 42074994 - Non-Mineral Antioxidant Supplementation in Endometriosis: Biological Rationale, Clinical Evidence, and Therapeutic Implications. Nutrients, 2026.
• PMID 41663453 - Administration of N-acetylcysteine influences the expression of apoptotic genes in granulosa cells of infertile women with endometriosis. Sci Rep, 2026.
• PMID 40647174 - Epigallocatechin Gallate as a Potential Therapeutic Agent in Endometriosis: A Narrative Review. Nutrients, 2025.
• PMID 41608512 - Therapeutic potential of epigallocatechin gallate in gynecologic cancer, endometriosis, PCOS. Front Nutr, 2025.
• PMID 41020814 - New Perspectives on the Use of Resveratrol in the Treatment of Metabolic and Estrogen-Dependent Conditions. Curr Issues Mol Biol, 2025.
• PMID 41797792 - From bench to bedside: unlocking the anti-inflammatory, antioxidant, and anticancer promise of curcumin in gynecology. Front Med, 2026.
• PMID 41373108 - Role of Phytoestrogens in Endometriosis. J Obstet Gynaecol Res, 2025.
• PMID 40404937 - Anti-infertility roles of flavonoids: insights into the female reproductive system. Mol Biol Rep, 2025.
• PMID 41715206 - The role of probiotics in the treatment of endometriosis (ProMetrioS): RCT protocol. Trials, 2026.
• PMID 41844737 - Efficacy of probiotic supplementation in reducing primary dysmenorrhea: a double-blinded RCT. Sci Rep, 2026.
• PMID 42210952 - Blood-invigorating Chinese herbal medicines plus conventional therapy for endometriosis: a network meta-analysis of 107 RCTs. Front Med, 2026.
• PMID 41754163 - The Role of Nutrition on the Pathogenesis of Endometriosis. Nutrients, 2026.
• PMID 40920291 - Effectiveness of Medical Nutrition Therapy in the Management of Patients with Obesity and Endometriosis. Curr Obes Rep, 2025.
• PMID 42191188 - Anti-inflammatory diet intervention and cognitive behavioural therapy in endometriosis: protocol for a randomised controlled clinical trial. BMJ Open, 2026.

Beloop, vruchtbaarheid en comorbiditeit

• PMID 42250374 - Endometriosis at the extremes of reproductive life: a life-course perspective on age-specific phenotypes. Eur J Obstet Gynecol Reprod Biol, 2026.
• PMID 41897338 - Endometriosis at the Single-Cell Level: Molecular Insights and Implications for Assisted Reproduction Success. Biomolecules, 2026.
• PMID 42160242 - ESPriT1: laparoscopic treatment of isolated superficial peritoneal endometriosis for chronic pelvic pain: a randomised controlled feasibility trial. Reprod Fertil, 2026.
• PMID 42222530 - A review on shared genetic architecture of endometriosis and migraine: from pleiotropy to convergent inflammatory pathways. Front Neurol, 2026.

Disclaimer

Dit dossier is een samenvatting van wetenschappelijke literatuur ten behoeve van professionals en geïnformeerde gebruikers. Het is geen medisch advies en vervangt geen consult, diagnose of behandeling door een arts. Beslissingen over medicatie, suppletie of leefstijl horen individueel met een zorgverlener te worden afgestemd.